Thursday, July 23, 2009
Understanding Types Of Malignant Mesothelioma
Understanding the Epithelial, Surcomatoid and the Biphasic types of the malignant mesothelioma
2009-07-22 - (mesotheliomacancernews.com - Mesothelioma Press Release) - Dallas, TX - Facts about mesothelioma cancer are fairly known to many and specially to those who are affected with mesothelioma cancer. Yet, with this rare disease harming those who have been closely associated with asbestos, exposing themselves to asbestos fibers at their work place or through the family members who brought the dust of silver fiber at home in the work cloths, shoes, hair while returing from work.
The fact noted here is that no one who comes into contact with asbestos is spared from its lethal effects whether its is a direct asbestos industry workers or the worker of the industry that produces goods in which asbestos is used as a raw material and the family members, their friends and loved ones of these workers. Thus, the number of people who get effected from asbestos fibers easily and surely multiplies.
Epithelial mesothelioma, Sarcomatoid mesothelioma, malignant biphasic mesothelioma
1) The Epithelial mesothelioma: Approximately 50% to 70% of mesothelioma cells are the epithelial cells. These cells are tubular in pattern and are of uniform shape. These cells develop in the mesothelioma that protects certain organs of the gastrointestinal tract and the lungs.
Treatment of these epithelial cells is based on the three traditional therapies of surgery, radiation and chemotherapy. Sometimes, two therapies are combined for the treatment, depending upon the intensity of the infection.
2) The sarcomatoid mesothelioma: These cells are irregular and oval in shape. The nucleus is difficult to detect. These cells further divide into secondary cells and are classified as the 'acinar 'cells, the' clear'' cells and the 'tubo-papillary' cells. About 10% to 15% of the total mesothelioma cancer patients belong to this class of cells. This type of the cells lead towards death.
The treatment is the same as of the mesothelioma epithelial cells. But, these sarcomatoid cells are very resistant to these treatments. Help of other therapies such as the immunotherapy, the gene therapy and the photodynamic therapy proves helpful.
3) The malignant biphasic mesothelioma: 40% to 60% of the mesothelioma cancer patients belong to this class, The biphasic system is a combination of both the epithelial and the sarcomatoid types of mesothelioma.
Treatment is the same as prescribes for the above two types, with a few variations, depending upon the stage and level of the disease.
Thus, with the knowledge and the development in treatment and therapies, the sad part is, that all mesothelioma cancer cases are fatal.
Monday, June 01, 2009
Drug Toxicity Assay Kits Increase Drug Development Efficiency
Bioo Scientific's Toxicity Assay Kits Increase the Efficiency of Drug Development
Bioo Scientific announced the launch of the MaxDiscoveryT Toxicity Assay Kits for the monitoring of toxic effects in in vivo preclinical studies.
Austin, TX, May 31, 2009 -- Since toxicity is one of the leading causes of drug failures, measuring preclinical toxicity is a critical drug development function. Accurate in vivo toxicity assays are essential to lowering attrition and increasing efficiency in drug development.
Bioo Scientific announced today the launch of their MaxDiscoveryT Toxicity Assay Kits. These kits monitor in vivo toxicity by measuring liver and heart function in serum samples. They provide simple, convenient, colorimetric determination of well-characterized functional markers of for liver and heart. They are ideal tools to monitor toxic effects caused by administration of siRNA, DNA plasmids, transfection agents or other therapeutic treatments during preclinical studies. The assays can be used in a range of mammals, including mice and rats, providing a powerful tool to assess and reduce the toxicity of drugs formulations and to improve drug delivery methods.
According to Dr Joe Krebs, Director of Protein Chemistry and Engineering at Bioo Scientific, "MaxDiscoveryT Toxicity kits are designed to provide researchers with rapid, cost-effective tools required to address the escalating challenges of drug development in today's competitive landscape."
Assays are available for alanine transaminase, aspartate transminase, alkaline phosphatase, lactate dehydrogenase, cholesterol, and creatine kinase.
About Bioo Scientific
Bioo Scientific Corporation is a global biotechnology tools company, headquartered in Austin, Texas. Bioo Scientific provides innovative products and services to academic researchers, pharmaceutical and biotechnology companies, molecular diagnostics laboratories, and customers who perform food and feed safety analysis.
Contact Information
Bioo Scientific
Dawn Obermoeller
512-301-4094
dawn@redbridgemarketing.com
www.biooscientific.com
